June 2019
Continuous synthesis of the pyridone in route to dolutegravir
Medicines for all
April 2019
Synthesis of 5-Fluorocytosine Using 2-Cyano-2-fluoroethenolate as a Key Intermediate
Jule-Philipp Dietz, Brenden P. Derstine, Dorota Ferenc, Evan T. Crawford, Anthony J. Arduengo III, B. Frank Gupton, D. Tyler McQuade, and Till Opatz
March 2019
A Holistic Approach to Streamlining Pharmaceutical Processes: A Conversation
B. Frank Gupton and D. Tyler McQuade
January 2019
5-fluorocytosine
Medicines for all
January 2019
Process Design and Optimization for the Continuous Manufacturing of Nevirapine, an Active Pharmaceutical Ingredient for HIV Treatment
Samir Diab, D. Tyler McQuade, B. Frank Gupton, and Dimitrios I. Gerogiorgis
May 2018
7-Step Flow Synthesis of the HIV Integrase Inhibitor Dolutegravir
Robert E. Ziegler, Bimbisar K. Desai, Jo-Ann Jee, B. Frank Gupton, Thomas D. Roper, and Timothy F. Jamison
May 2017
Increasing global access to the high-volume HIV drug nevirapine through process intensification
Jenson Verghese, Caleb J. Kong, Daniel Rivalti, Eric C. Yu, Rudy Krack, Jesus Alcázar, Julie B. Manley, D. Tyler McQuade, Saeed Ahmad, Katherine Belecki and B. Frank Gupton
May 2015
The Medicines for All Initiative: the nevirapine process optimization
Medicines for all
November 2015
The Medicines for All Initiative: continuous synthesis of nevirapine and reaction monitoring with online PAT
Medicines for all